Search on: C3 ACTIVATOR 
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Descriptor English:   Complement C3-C5 Convertases 
Descriptor Spanish:   Convertasas de Complemento C3-C5 
Descriptor Portuguese:   Convertases de Complemento C3-C5 
Synonyms English:   C 3 Convertase
C3 Activator
C3-C5 Convertase
C5 Cleaving Enzyme
C5 Convertase
Complement 3 Convertase
Complement 5 Convertase
Complement C3 Convertases
Complement C5 Convertases
Activator, C3
C3 C5 Convertase
C3 Convertases, Complement
C3-C5 Convertases, Complement
C5 Convertases, Complement
Complement C3 C5 Convertases
Convertase, C 3
Convertase, C3
Convertase, C3-C5
Convertase, Complement 3
Convertases, Complement C3
Convertases, Complement C3-C5
Convertases, Complement C5
C3 Convertase  
Tree Number:   D12.776.124.486.274.045.387
Definition English:   Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50828 
Unique Identifier:   D050577 

Occurrence in VHL: 		 

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